Design and statistical optimization of an effervescent floating drug delivery system of theophylline using response surface methodology

Design and statistical optimization of an effervescent floating drug delivery system of theophylline using response surface methodology

The aim of this research was to formulate effervescent floating drug delivery systems of theophylline using different release retarding polymers such as ethyl cellulose, Eudragit® L100, xanthan gum and polyethylene oxide (PEO) N12K. Sodium bicarbonate was used as a gas generating agent. Direct compr...

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Bibliographic Details
Main Authors: Srikanth Meka Venkata, Ee Li Chew, Sheshala Ravi
Format: Article
Language:English
Published: Sciendo 2016-03-01
Series:Acta Pharmaceutica
Subjects:
theophylline
gastroretentive
floating
central composite
peo n12k
Online Access:https://doi.org/10.1515/acph-2016-0002

Internet

https://doi.org/10.1515/acph-2016-0002

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