β-Catenin Does Not Confer Tumorigenicity When Introduced into Partially Transformed Human Mesenchymal Stem Cells

β-Catenin Does Not Confer Tumorigenicity When Introduced into Partially Transformed Human Mesenchymal Stem Cells

Although osteosarcoma is the most common primary malignant bone tumor in children and adolescents, its cell of origin and the genetic alterations are unclear. Previous studies have shown that serially introducing hTERT, SV40 large TAg, and H-Ras transforms human mesenchymal stem cells into two disti...

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Bibliographic Details
Main Authors: Sajida Piperdi, Lukas Austin-Page, David Geller, Manpreet Ahluwalia, Sarah Gorlick, Jonathan Gill, Amy Park, Wendong Zhang, Nan Li, So Hak Chung, Richard Gorlick
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2012/164803

Internet

http://dx.doi.org/10.1155/2012/164803

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