Estimating the predictive power of silent mutations on cancer classification and prognosis

Abstract In recent years it has been shown that silent mutations, in and out of the coding region, can affect gene expression and may be related to tumorigenesis and cancer cell fitness. However, the predictive ability of these mutations for cancer type diagnosis and prognosis has not been evaluated...

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Bibliographic Details
Main Authors: Tal Gutman, Guy Goren, Omri Efroni, Tamir Tuller
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-021-00229-1