Contribution by polymorphonucleate granulocytes to elevated gamma-glutamyltransferase in cystic fibrosis sputum.

BACKGROUND: Cystic fibrosis (CF) is an autosomal recessive disorder characterized by a chronic neutrophilic airways inflammation, increasing levels of oxidative stress and reduced levels of antioxidants such as glutathione (GSH). Gamma-glutamyltransferase (GGT), an enzyme induced by oxidative stress...

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Bibliographic Details
Main Authors: Alessandro Corti, Maria Franzini, Silvana Cianchetti, Gabriella Bergamini, Evelina Lorenzini, Paola Melotti, Aldo Paolicchi, Pierluigi Paggiaro, Alfonso Pompella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3319600?pdf=render