On an enhancement of RNA probing data using information theory
Abstract Identifying the secondary structure of an RNA is crucial for understanding its diverse regulatory functions. This paper focuses on how to enhance target identification in a Boltzmann ensemble of structures via chemical probing data. We employ an information-theoretic approach to solve the p...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-08-01
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Series: | Algorithms for Molecular Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13015-020-00176-z |