On an enhancement of RNA probing data using information theory

Abstract Identifying the secondary structure of an RNA is crucial for understanding its diverse regulatory functions. This paper focuses on how to enhance target identification in a Boltzmann ensemble of structures via chemical probing data. We employ an information-theoretic approach to solve the p...

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Bibliographic Details
Main Authors: Thomas J. X. Li, Christian M. Reidys
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Algorithms for Molecular Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13015-020-00176-z