Attenuation and efficacy of live-attenuated Rift Valley fever virus vaccine candidates in non-human primates.

Rift Valley fever virus (RVFV) is an important mosquito-borne veterinary and human pathogen that has caused large outbreaks of severe disease throughout Africa and the Arabian Peninsula. Currently, no licensed vaccine or therapeutics exists to treat this potentially deadly disease. The explosive nat...

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Bibliographic Details
Main Authors: Darci R Smith, Sara C Johnston, Ashley Piper, Miriam Botto, Ginger Donnelly, Joshua Shamblin, César G Albariño, Lisa E Hensley, Connie Schmaljohn, Stuart T Nichol, Brian H Bird
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5962102?pdf=render