SARS-CoV-2 Envelope (E) protein interacts with PDZ-domain-2 of host tight junction protein ZO1.

SARS-CoV-2 Envelope (E) protein interacts with PDZ-domain-2 of host tight junction protein ZO1.

Newly emerged SARS-CoV-2 is the cause of an ongoing global pandemic leading to severe respiratory disease in humans. SARS-CoV-2 targets epithelial cells in the respiratory tract and lungs, which can lead to amplified chloride secretion and increased leak across epithelial barriers, contributing to s...

Full description

Bibliographic Details
Main Authors: Ariel Shepley-McTaggart, Cari A Sagum, Isabela Oliva, Elizabeth Rybakovsky, Katie DiGuilio, Jingjing Liang, Mark T Bedford, Joel Cassel, Marius Sudol, James M Mullin, Ronald N Harty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0251955

Internet

https://doi.org/10.1371/journal.pone.0251955

Similar Items