Tumor Burden and Intraosseous Metabolic Activity as Predictors of Bone Marrow Failure during Radioisotope Therapy in Metastasized Prostate Cancer Patients

Rationale. Radium-223-Dichloride (Ra-223) is an alpha-emitter, used to treat bone metastases. Patients with high metastatic burden and/or with increased trabecular bone uptake could present a higher incidence of hematologic toxicity. We hypothesized that these two factors are predictors of bone marr...

Full description

Bibliographic Details
Main Authors: Francesco Fiz, Samine Sahbai, Cristina Campi, Matthias Weissinger, Helmut Dittmann, Cecilia Marini, Michele Piana, Gianmario Sambuceti, Christian la Fougère
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/3905216