Updating the salivary gland transcriptome of Phlebotomus papatasi (Tunisian strain): the search for sand fly-secreted immunogenic proteins for humans.

Updating the salivary gland transcriptome of Phlebotomus papatasi (Tunisian strain): the search for sand fly-secreted immunogenic proteins for humans.

Sand fly saliva plays an important role in both blood feeding and outcome of Leishmania infection. A cellular immune response against a Phlebotomus papatasi salivary protein was shown to protect rodents against Leishmania major infection. In humans, P. papatasi salivary proteins induce a systemic ce...

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Bibliographic Details
Main Authors: Maha Abdeladhim, Ryan C Jochim, Melika Ben Ahmed, Elyes Zhioua, Ifhem Chelbi, Saifedine Cherni, Hechmi Louzir, José M C Ribeiro, Jesus G Valenzuela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3491003?pdf=render

Internet

http://europepmc.org/articles/PMC3491003?pdf=render

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