Characterization of HA-tagged α9 and α10 nAChRs in the mouse cochlea

Abstract Neurons of the medial olivary complex inhibit cochlear hair cells through the activation of α9α10-containing nicotinic acetylcholine receptors (nAChRs). Efforts to study the localization of these proteins have been hampered by the absence of reliable antibodies. To overcome this obstacle, C...

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Bibliographic Details
Main Authors: Pankhuri Vyas, Megan Beers Wood, Yuanyuan Zhang, Adam C. Goldring, Fatima-Zahra Chakir, Paul Albert Fuchs, Hakim Hiel
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78380-5