In-silico design of new enalapril analogs (ACE inhibitors) using QSAR and molecular docking models
Angiotensin-converting-enzyme inhibitors (ACEI) are a group of drugs primarily used in the treatment of cardiovascular disease. In this study, MLR and PLS QSAR models were developed to evaluate the antihypertensive activity of new enalapril analogs, while binding affinities between each analog and A...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-01-01
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| Series: | Informatics in Medicine Unlocked |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914820300149 |