Functional network endophenotypes unravel the effects of apolipoprotein E epsilon 4 in middle-aged adults.

Functional network endophenotypes unravel the effects of apolipoprotein E epsilon 4 in middle-aged adults.

Apolipoprotein E-ε4 (APOE-ε4) accentuates memory decline, structural volume loss and cerebral amyloid deposition in cognitively healthy adults. We investigated whether APOE-ε4 carriers will show disruptions in the intrinsic cognitive networks, including the default mode (DMN), executive control (ECN...

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Bibliographic Details
Main Authors: Joseph S Goveas, Chunming Xie, Gang Chen, Wenjun Li, B Douglas Ward, Malgorzata B Franczak, Jennifer L Jones, Piero G Antuono, Shi-Jiang Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3570545?pdf=render

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http://europepmc.org/articles/PMC3570545?pdf=render

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