Deficiency of retinaldehyde dehydrogenase 1 induces BMP2 and increases bone mass in vivo.

The effects of retinoids, the structural derivatives of vitamin A (retinol), on post-natal peak bone density acquisition and skeletal remodeling are complex and compartment specific. Emerging data indicates that retinoids, such as all trans retinoic acid (ATRA) and its precursor all trans retinaldeh...

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Bibliographic Details
Main Authors: Shriram Nallamshetty, Hong Wang, Eun-Jung Rhee, Florian W Kiefer, Jonathan D Brown, Sutada Lotinun, Phuong Le, Roland Baron, Clifford J Rosen, Jorge Plutzky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3739807?pdf=render