H3K4me3 Is a Potential Mediator for Antiproliferative Effects of Calcitriol (1α,25(OH)2D3) in Ovarian Cancer Biology

H3K4me3 Is a Potential Mediator for Antiproliferative Effects of Calcitriol (1α,25(OH)2D3) in Ovarian Cancer Biology

Posttranslational histone modification plays an important role in tumorigenesis. Histone modification is a dynamic response of chromatin to various signals, such as the exposure to calcitriol (1&#945;,25(OH)<sub>2</sub>D<sub>3</sub>). Recent studies suggested that histone...

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Bibliographic Details
Main Authors: Nan Han, Udo Jeschke, Christina Kuhn, Anna Hester, Bastian Czogalla, Sven Mahner, Miriam Rottmann, Doris Mayr, Elisa Schmoeckel, Fabian Trillsch
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
ovarian cancer
histone 3 lysine 4 trimethylation (h3k4me3)
histone modification
calcitriol
1α,25(oh)<sub>2</sub>d<sub>3</sub>
prognosis
vitamin d receptor
cell proliferation
Online Access:https://www.mdpi.com/1422-0067/21/6/2151

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https://www.mdpi.com/1422-0067/21/6/2151

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