Oxidation of HDAC4 by Nox4-derived H2O2 maintains tube formation by endothelial cells
NADPH oxidases produce reactive oxygen species that differ in localization, type and concentration. Within the Nox family only Nox4 produces H2O2 which can directly oxidize cysteine residues. With this post-translational modification, activity, stability, localization and protein-protein interaction...
Main Authors: | Tim Schader, Oliver Löwe, Christina Reschke, Pedro Malacarne, Fabian Hahner, Niklas Müller, Anna Gajos-Draus, Johannes Backs, Katrin Schröder |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231720308740 |
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