Enhancing the Efficacy of Stem Cell Therapy with Glycosaminoglycans

Enhancing the Efficacy of Stem Cell Therapy with Glycosaminoglycans

Summary: Human mesenchymal stem cell (hMSC) therapy offers significant potential for osteochondral regeneration. Such applications require their ex vivo expansion in media frequently supplemented with fibroblast growth factor 2 (FGF2). Particular heparan sulfate (HS) fractions stabilize FGF2-FGF rec...

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Bibliographic Details
Main Authors: Ling Ling, Xiafei Ren, Xue Cao, Afizah Binte Mohd Hassan, Sophia Mah, Padmapriya Sathiyanathan, Raymond A.A. Smith, Clarissa L.L. Tan, Michelle Eio, Rebekah M. Samsonraj, Andre J. van Wijnen, Michael Raghunath, Victor Nurcombe, James H. Hui, Simon M. Cool
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119304175

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http://www.sciencedirect.com/science/article/pii/S2213671119304175

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