Tissue tropisms opt for transmissible reassortants during avian and swine influenza A virus co-infection in swine.

Genetic reassortment between influenza A viruses (IAVs) facilitate emergence of pandemic strains, and swine are proposed as a "mixing vessel" for generating reassortants of avian and mammalian IAVs that could be of risk to mammals, including humans. However, how a transmissible reassortant...

Full description

Bibliographic Details
Main Authors: Xiaojian Zhang, Hailiang Sun, Fred L Cunningham, Lei Li, Katie Hanson-Dorr, Matthew W Hopken, Jim Cooley, Li-Ping Long, John A Baroch, Tao Li, Brandon S Schmit, Xiaoxu Lin, Alicia K Olivier, Richard G Jarman, Thomas J DeLiberto, Xiu-Feng Wan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007417