Structure and mechanism of DNA delivery of a gene transfer agent

Gene transfer agents (GTAs) are phage-like particles that mediate lateral gene exchange. Here, the authors provide the structure of the GTA of Rhodobacter capsulatus (RcGTA), which resembles a tailed phage, and describe the conformational changes required for DNA ejection.

Bibliographic Details
Main Authors: Pavol Bárdy, Tibor Füzik, Dominik Hrebík, Roman Pantůček, J. Thomas Beatty, Pavel Plevka
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16669-9