Effect of ABCB1 3435C>T transporter gene polymorphism on plasma efavirenz concentration in HIV-1 infected Thai adults

Effect of ABCB1 3435C>T transporter gene polymorphism on plasma efavirenz concentration in HIV-1 infected Thai adults

Objective: To investigate the influence of ABCB1 polymorphisms on the plasma level of efavirenz in Thai adult cases infected with HIV-1. Methods: A single nucleotide polymorphism of ABCB1 3435C>T (rs1045642) in the gene encoding ABCB1 was genotyped using real-time PCR-based alleles in 149 HIV-inf...

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Bibliographic Details
Main Authors: Sahapat Barusrux, Napatrupron Koomdee, Rattanaporn Sukprasong, Weerawat Manosuthi, Monpat Chamnanphon, Apichaya Puangpetch, Chonlaphat Sukasem, Veeranoot Nissapatorn, Maria de Lourdes Pereira
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Asian Pacific Journal of Tropical Medicine
Subjects:
transporter gene; abcb1 3435c>t; efavirenz; hiv-1; thai
Online Access:http://www.apjtm.org/article.asp?issn=1995-7645;year=2020;volume=13;issue=6;spage=266;epage=271;aulast=Barusrux

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http://www.apjtm.org/article.asp?issn=1995-7645;year=2020;volume=13;issue=6;spage=266;epage=271;aulast=Barusrux

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