Investigations on the Solubility of Vortioxetine Based on X-ray Structural Data and Crystal Contacts

Investigation on the solid-state pharmaceutical chemistry has been known as an intriguing strategy to not only modify the physicochemical properties of drugs but also expand the solid form landscape. Vortioxetine (VOT) is an effective but poorly soluble antidepressant. To improve the solubility of v...

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Bibliographic Details
Main Authors: Xian-Rui Zhang, Lei Gao, Gui-Yuan He, Chao-Jie Chen
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/9/10/536