Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression.

Alzheimer's disease (AD) is a complex multifactorial disorder with poorly characterized pathogenesis. Our understanding of this disease would thus benefit from an approach that addresses this complexity by elucidating the regulatory networks that are dysregulated in the neural compartment of AD...

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Bibliographic Details
Main Authors: Soline Aubry, William Shin, John F Crary, Roger Lefort, Yasir H Qureshi, Celine Lefebvre, Andrea Califano, Michael L Shelanski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4363671?pdf=render