Identification of a novel class of ω,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis

Identification of a novel class of ω,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis

We have identified an ω,E,E-farnesyl diphosphate (ω,E,E-FPP) synthase, encoded by the open reading frame Rv3398c, from Mycobacterium tuberculosis that is unique among reported FPP synthases in that it does not contain the type I (eukaryotic) or the type II (eubacterial) ω,E,E-FPP synthase signature...

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Bibliographic Details
Main Authors: Rakesh K. Dhiman, Mark C. Schulbach, Sebabrata Mahapatra, Alain R. Baulard, Varalakshmi Vissa, Patrick J. Brennan, Dean C. Crick
Format: Article
Language:English
Published: Elsevier 2004-06-01
Series:Journal of Lipid Research
Subjects:
dimethylallyl diphosphate
mycobacterial expression vector
short-chain prenyl diphosphate synthase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318125

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http://www.sciencedirect.com/science/article/pii/S0022227520318125

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