Effect of xanthan gum-based food thickeners on the dissolution profile of fluoroquinolones oral formulations

Effect of xanthan gum-based food thickeners on the dissolution profile of fluoroquinolones oral formulations

Abstract Background Xanthan gum-based food thickeners (XG-FTs) are often ingested by patients with dysphagia to prevent aspiration during drug treatment. Reportedly, XG-FTs affect tablet disintegration, drug dissolution rates, and reduce the efficacy of postprandial antihyperglycemic agents. The abs...

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Bibliographic Details
Main Authors: Nobuyuki Takahashi, Yoshiaki Fujita, Nanako Takahashi, Akihiro Nakamura, Tsutomu Harada
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Fluoroquinolone
Xanthan gum
Film coating
Ciprofloxacin
Food thickener
Dissolution test
Online Access:https://doi.org/10.1186/s40780-020-00181-9

Internet

https://doi.org/10.1186/s40780-020-00181-9

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