Bisphosphonates reduce biomaterial turnover in healing of critical-size rat femoral defects

Treatment of osteoporotic patients with bisphosphonates (BPs) preserves bone mass and microarchitecture. The high prescription rate of the drugs brings about increases in the numbers of fractures and bone defects requiring surgical interventions in these patients. Currently, critical-size defects ar...

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Bibliographic Details
Main Authors: Michel Hauser, Mark Siegrist, Alain Denzer, Nikola Saulacic, Joël Grosjean, Marc Bohner, Willy Hofstetter
Format: Article
Language:English
Published: SAGE Publishing 2018-10-01
Series:Journal of Orthopaedic Surgery
Online Access:https://doi.org/10.1177/2309499018802487