NANOG priming before full reprogramming may generate germ cell tumours

NANOG priming before full reprogramming may generate germ cell tumours

Reprogramming somatic cells into a pluripotent state brings patient-tailored, ethical controversy-free cellular therapy closer to reality. However, stem cells and cancer cells share many common characteristics; therefore, it is crucial to be able to discriminate between them. We generated two induce...

Full description

Bibliographic Details
Main Authors: I Grad, Y Hibaoui, M Jaconi, L Chicha, R Bergström-Tengzelius, MR Sailani, MF Pelte, S Dahoun, TA Mitsiadis, V Töhönen, S Bouillaguet, SE Antonarakis, J Kere, M Zucchelli, O Hovatta, A Feki
Format: Article
Language:English
Published: AO Research Institute Davos 2011-11-01
Series:European Cells & Materials
Subjects:
Induced pluripotent stem cells
stem cells
cancer stem cells
NANOG
cancer
germ-cell tumour
reprogramming
pluripotency
Online Access:http://www.ecmjournal.org/journal/papers/vol022/pdf/v022a20.pdf

Internet

http://www.ecmjournal.org/journal/papers/vol022/pdf/v022a20.pdf

Similar Items