Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA.

Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA.

To address the role of translationally active HIV reservoir in chronic inflammation and non-AIDS related disorders, we first need a simple and accurate assay to evaluate viral protein expression in virally suppressed subjects.We optimized an HIV Nef enzyme-linked immunosorbent assay (ELISA) and used...

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Bibliographic Details
Main Authors: Jana Ferdin, Katja Goričar, Vita Dolžan, Ana Plemenitaš, Jeffrey N Martin, Boris M Peterlin, Steven G Deeks, Metka Lenassi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5783402?pdf=render

Internet

http://europepmc.org/articles/PMC5783402?pdf=render

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