Multicomponent Synthesis of Polyphenols and Their In Vitro Evaluation as Potential β-Amyloid Aggregation Inhibitors

Multicomponent Synthesis of Polyphenols and Their In Vitro Evaluation as Potential β-Amyloid Aggregation Inhibitors

While plant polyphenols possess a variety of biological properties, exploration of chemical diversity around them is still problematic. Here, an example of application of the Ugi multicomponent reaction to the combinatorial assembly of artificial, yet “natural-like”, polyphenols...

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Bibliographic Details
Main Authors: Denise Galante, Luca Banfi, Giulia Baruzzo, Andrea Basso, Cristina D’Arrigo, Dario Lunaccio, Lisa Moni, Renata Riva, Chiara Lambruschini
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
multicomponent reactions
polyphenols
β-amyloid proteins
Alzheimer’s disease
Ugi reaction
β-lactams
Online Access:https://www.mdpi.com/1420-3049/24/14/2636

Internet

https://www.mdpi.com/1420-3049/24/14/2636

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