Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300
Aging: toward a natural treatment for osteoarthritis The naturally occurring small molecule spermidine might prevent and repair the cartilage damage in osteoarthritis, commonly associated with aging. Spermidine was first found in semen but is widely distributed in animals and plants and is known to...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-09-01
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| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-018-0149-3 |