ACYP2 contributes to malignant progression of glioma through promoting Ca2+ efflux and subsequently activating c-Myc and STAT3 signals

ACYP2 contributes to malignant progression of glioma through promoting Ca2+ efflux and subsequently activating c-Myc and STAT3 signals

Abstract Background Acylphosphatase 2 (ACYP2) is involved in cell differentiation, energy metabolism and hydrolysis of intracellular ion pump. It has been reported as a negative regulator in leukemia and a positive regulator in colon cancer, respectively. However, its biological role in glioma remai...

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Bibliographic Details
Main Authors: Mengdan Li, Banjun Ruan, Jing Wei, Qi Yang, Mingwei Chen, Meiju Ji, Peng Hou
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Glioma
Acylphosphatase 2 (ACYP2)
Calcium homeostasis
C-Myc
STAT3
Online Access:http://link.springer.com/article/10.1186/s13046-020-01607-w

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http://link.springer.com/article/10.1186/s13046-020-01607-w

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