HIV-1-Based Virus-like Particles that Morphologically Resemble Mature, Infectious HIV-1 Virions

A prophylactic vaccine eliciting both broad neutralizing antibodies (bNAbs) to the HIV-1 envelope glycoprotein (Env) and strong T cell responses would be optimal for preventing HIV-1 transmissions. Replication incompetent HIV-1 virus-like particles (VLPs) offer the opportunity to present authentic-s...

Full description

Bibliographic Details
Main Authors: Christopher A. Gonelli, Georges Khoury, Rob J. Center, Damian F.J. Purcell
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Viruses
Subjects:
VLP
Online Access:https://www.mdpi.com/1999-4915/11/6/507