Radical Change in Zoonotic Abilities of Atypical BSE Prion Strains as Evidenced by Crossing of Sheep Species Barrier in Transgenic Mice

Radical Change in Zoonotic Abilities of Atypical BSE Prion Strains as Evidenced by Crossing of Sheep Species Barrier in Transgenic Mice

Classical bovine spongiform encephalopathy (BSE) is the only zoonotic prion disease described to date. Although the zoonotic potential of atypical BSE prions have been partially studied, an extensive analysis is still needed. We conducted a systematic study by inoculating atypical BSE isolates from...

Full description

Bibliographic Details
Main Authors: Alba Marín-Moreno, Alvina Huor, Juan Carlos Espinosa, Jean Yves Douet, Patricia Aguilar-Calvo, Naima Aron, Juan Píquer, Sévérine Lugan, Patricia Lorenzo, Cecile Tillier, Hervé Cassard, Olivier Andreoletti, Juan María Torres
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2020-06-01
Series:Emerging Infectious Diseases
Subjects:
transmissible spongiform encephalopathies
prion
atypical bovine spongiform encephalopathy
BSE
Val129-PrP
transmission barrier
Online Access:https://wwwnc.cdc.gov/eid/article/26/6/18-1790_article

Internet

https://wwwnc.cdc.gov/eid/article/26/6/18-1790_article

Similar Items