In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [18F]DPA714 PET

In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [18F]DPA714 PET

Abstract Background Over the past decades, positron emission tomography (PET) imaging has become an increasingly useful research modality in the field of multiple sclerosis (MS) research, as PET can visualise molecular processes, such as neuroinflammation, in vivo. The second generation PET radiolig...

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Bibliographic Details
Main Authors: Marloes H. J. Hagens, Sandeep V. Golla, Martijn T. Wijburg, Maqsood Yaqub, Dennis Heijtel, Martijn D. Steenwijk, Patrick Schober, John J. P. Brevé, Robert C. Schuit, Tristan A. Reekie, Michael Kassiou, Anne-Marie van Dam, Albert D. Windhorst, Joep Killestein, Frederik Barkhof, Bart N. M. van Berckel, Adriaan A. Lammertsma
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Neuroinflammation
Subjects:
[18F]DPA714
Multiple sclerosis
Neuroinflammation
Positron emission tomography
TSPO
Online Access:http://link.springer.com/article/10.1186/s12974-018-1352-9

Internet

http://link.springer.com/article/10.1186/s12974-018-1352-9

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