Evolutionary history of the PER3 variable number of tandem repeats (VNTR): idiosyncratic aspect of primate molecular circadian clock.

The PER3 gene is one of the clock genes, which function in the core mammalian molecular circadian system. A variable number of tandem repeats (VNTR) locus in the 18th exon of this gene has been strongly associated to circadian rhythm phenotypes and sleep organization in humans, but it has not been i...

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Main Authors: Flávia Cal Sabino, Amanda Oliveira Ribeiro, Sérgio Tufik, Laila Brito Torres, José Américo Oliveira, Luiz Eugênio Araújo Moraes Mello, Jeferson Souza Cavalcante, Mario Pedrazzoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4164614?pdf=render