Identifying Small Molecules That Promote Quasipalindrome-Associated Template-Switch Mutations in Escherichia coli
DNA can assemble into non-B form structures that stall replication and cause genomic instability. One such secondary structure results from an inverted DNA repeat that can assemble into hairpin and cruciform structures during DNA replication. Quasipalindromes (QP), imperfect inverted repeats, are si...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2020-05-01
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Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.120.401106 |