Temporal and spatial requirements of unplugged/MuSK function during zebrafish neuromuscular development.

One of the earliest events in neuromuscular junction (NMJ) development is the accumulation of acetylcholine receptor (AChR) at the center of muscle cells. The unplugged/MuSK (muscle specific tyrosine kinase) gene is essential to initiate AChR clustering but also to restrict approaching growth cones...

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Bibliographic Details
Main Authors: Lili Jing, Laura R Gordon, Elena Shtibin, Michael Granato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2809748?pdf=render