Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease

Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease

Synaptic neurodegeneration is thought to be an early event initiated by soluble β-amyloid (Aβ) aggregates that closely correlates with cognitive decline in Alzheimer disease (AD). Apolipoprotein ε4 (APOE4) is the most common genetic risk factor for both familial AD (FAD) and sporadic AD; it accelera...

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Bibliographic Details
Main Authors: Qiu-Lan Ma, Edmond Teng, Xiaohong Zuo, Mychica Jones, Bruce Teter, Evan Y. Zhao, Cansheng Zhu, Tina Bilousova, Karen H. Gylys, Liana G. Apostolova, Mary Jo LaDu, Mir Ahamed Hossain, Sally A. Frautschy, Gregory M. Cole
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Neurobiology of Disease
Subjects:
Alzheimer disease
β-amyloid
Plasma biomarkers
Neuronal pentraxin 1
APOE
MCI
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118300469

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http://www.sciencedirect.com/science/article/pii/S0969996118300469

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