Efficacy of topical and systemic transplantation of mesenchymal stem cells in a rat model of diabetic ischemic wounds

Efficacy of topical and systemic transplantation of mesenchymal stem cells in a rat model of diabetic ischemic wounds

Abstract Background Mesenchymal stem cells (MSCs) exert positive effects in chronic wounds. However, critical parameters, such as the most effective administration routes, remain unclear. Accordingly, the purpose of this study was to compare the effects of topical and systemic transplantation MSCs o...

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Bibliographic Details
Main Authors: Jianxin Yan, Jiaji Liang, Yingxuan Cao, Mariya M. El Akkawi, Xuan Liao, Xiaojia Chen, Chengzhi Li, Kecheng Li, Guanghui Xie, Hongwei Liu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Stem Cell Research & Therapy
Subjects:
Bone marrow-derived mesenchymal stem cells
Type 2 diabetes mellitus
Critical limb ischemia
Diabetic foot ulcers
Chronic wounds
Online Access:https://doi.org/10.1186/s13287-021-02288-8

Internet

https://doi.org/10.1186/s13287-021-02288-8

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