Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer

Abstract Background Lung cancer is the leading cause of cancer related deaths and its incidence is highly correlated with cigarette smoking. Nicotine, the addictive component of tobacco smoke, cannot initiate tumors, but can promote proliferation, migration, and invasion of cells in vitro and promot...

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Bibliographic Details
Main Authors: Courtney M Schaal, Namrata Bora-Singhal, Durairaj Mohan Kumar, Srikumar P Chellappan
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-018-0901-2