In vitro and in vivo growth inhibition of human acute promyelocytic leukemia HL-60 cells by Guatteria megalophylla Diels (Annonaceae) leaf essential oil

In vitro and in vivo growth inhibition of human acute promyelocytic leukemia HL-60 cells by Guatteria megalophylla Diels (Annonaceae) leaf essential oil

Guatteria megalophylla Diels (Annonaceae) is an 8−10 m tall tree that grows near streams and is widely spread throughout Colombian, Ecuadorian, Peruvian, Brazilian and Guianese Amazon rainforest. Herein, we investigated for the first time the chemical composition and in vitro and in vivo anti-leukem...

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Bibliographic Details
Main Authors: Rafaela G.A. Costa, Talita A. da Anunciação, Morgana de S. Araujo, César A. Souza, Rosane B. Dias, Caroline B.S. Sales, Clarissa A.G. Rocha, Milena B.P. Soares, Felipe M.A. da Silva, Hector H.F. Koolen, Emmanoel V. Costa, Daniel P. Bezerra
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Guatteria megalophylla
Essential oil
Spathulenol
Anti-leukemia
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219353351

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http://www.sciencedirect.com/science/article/pii/S0753332219353351

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