Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway.

Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway.

Cell adhesion, migration and invasion are critical steps for carcinogenesis and cancer metastasis. Ganoderma lucidum, also called Lingzhi in China, is a traditional Chinese medicine, which exhibits anti-proliferation, anti-inflammation and anti-metastasis properties. Herein, GAEE, G. lucidum extract...

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Bibliographic Details
Main Authors: Guo-Sheng Wu, Yue-Lin Song, Zhi-Qi Yin, Jia-Jie Guo, Sheng-Peng Wang, Wen-Wen Zhao, Xiu-Ping Chen, Qing-Wen Zhang, Jin-Jian Lu, Yi-Tao Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3812178?pdf=render

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http://europepmc.org/articles/PMC3812178?pdf=render

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