Resveratrol acts via the mitogen-activated protein kinase (MAPK) pathway to protect retinal ganglion cells from apoptosis induced by hydrogen peroxide

The current study investigated the ability of resveratrol to protect RGC-5 retinal ganglion cells in culture against H2O2-induced apoptosis and the underlying mechanism of protection. RGC-5 cells were pre-exposed to resveratrol (5, 10, or 20 μM), followed by 200 μM H2O2. Cell viability and apoptosis...

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Bibliographic Details
Main Authors: Ming-jing Ye, Ni Meng
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
Online Access:http://dx.doi.org/10.1080/21655979.2021.1954742