RhoA as a Key Regulator of Innate and Adaptive Immunity

RhoA is a ubiquitously expressed cytoplasmic protein that belongs to the family of small GTPases. RhoA acts as a molecular switch that is activated in response to binding of chemokines, cytokines, and growth factors, and via mDia and the ROCK signaling cascade regulates the activation of cytoskeleta...

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Bibliographic Details
Main Authors: Matthias Bros, Katharina Haas, Lorna Moll, Stephan Grabbe
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/7/733