Purine Metabolites in Tumor-Derived Exosomes May Facilitate Immune Escape of Head and Neck Squamous Cell Carcinoma

Purine Metabolites in Tumor-Derived Exosomes May Facilitate Immune Escape of Head and Neck Squamous Cell Carcinoma

Body fluids of patients with head and neck squamous cell carcinoma (HNSCC) are enriched in exosomes that reflect properties of the tumor. The aim of this study was to determine whether purine metabolites are carried by exosomes and evaluate their role as potential contributors to tumor immune escape...

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Bibliographic Details
Main Authors: Nils Ludwig, Delbert G. Gillespie, Torsten E. Reichert, Edwin K. Jackson, Theresa L. Whiteside
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
exosomes
extracellular vesicles
TEX
HNSCC
head and neck cancer
purine metabolites
Online Access:https://www.mdpi.com/2072-6694/12/6/1602

Internet

https://www.mdpi.com/2072-6694/12/6/1602

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