A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft Tissue Sarcomas

The Hippo signaling pathway is an evolutionarily conserved developmental network vital for the regulation of organ size, tissue homeostasis, repair and regeneration, and cell fate. The Hippo pathway has also been shown to have tumor suppressor properties. Hippo transduction involves a series of kina...

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Bibliographic Details
Main Authors: Michael D Deel, Jenny J Li, Lisa E. S. Crose, Corinne M Linardic
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00190/full