ASYMMETRIC SULFOXIDATION OF ALBENDAZOLE TO RICOBENDAZOLE BY FUNGI: EFFECT OF pH

ASYMMETRIC SULFOXIDATION OF ALBENDAZOLE TO RICOBENDAZOLE BY FUNGI: EFFECT OF pH

Albendazole (ABZ) is an anthelmintic drug used for the treatment of infectious diseases in veterinary and human medicine. This drug is a prochiral drug that after administration, is rapidly oxidized in the pharmacologically active sulfoxide metabolite, which is also known as ricobendazole (ABZSOX)....

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Bibliographic Details
Main Authors: Thiago Barth, Viviane C. Hilário, Bruno A. Rocha, Niege A. J. C. Furtado, Mônica T. Pupo, Anderson R. M. de Oliveira
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2015-08-01
Series:Química Nova
Subjects:
albendazole
ricobendazole
enantiomeric excess
pH
stereoselective fungal transformation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422015000700944&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422015000700944&lng=en&tlng=en

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