Functional impairment of human myeloid dendritic cells during Schistosoma haematobium infection.

Chronic Schistosoma infection is often characterized by a state of T cell hyporesponsiveness of the host. Suppression of dendritic cell (DC) function could be one of the mechanisms underlying this phenomenon, since Schistosoma antigens are potent modulators of dendritic cell function in vitro. Yet,...

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Bibliographic Details
Main Authors: Bart Everts, Ayola A Adegnika, Yvonne C M Kruize, Hermelijn H Smits, Peter G Kremsner, Maria Yazdanbakhsh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2857749?pdf=render