Direct RNA-based detection and differentiation of CTX-M-type extended-spectrum β-lactamases (ESBL).

The current global spread of multi-resistant Gram-negatives, particularly extended spectrum β-lactamases expressing bacteria, increases the likelihood of inappropriate empiric treatment of critically ill patients with subsequently increased mortality. From a clinical perspective, fast detection of r...

Full description

Bibliographic Details
Main Authors: Claudia Stein, Oliwia Makarewicz, Yvonne Pfeifer, Christian Brandt, João Costa Ramos, Mareike Klinger, Mathias W Pletz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24224038/?tool=EBI