Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis.
A major goal of human genetics is to elucidate the genetic architecture of human disease, with the goal of fueling improvements in diagnosis and the understanding of disease pathogenesis. The degree to which epistasis, or non-additive effects of risk alleles at different loci, accounts for common di...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-04-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4849581?pdf=render |