Applying the D50 disease progression model to gray and white matter pathology in amyotrophic lateral sclerosis

Therapeutic management and research in Amyotrophic Laterals Sclerosis (ALS) have been limited by the substantial heterogeneity in progression and anatomical spread that are endemic of the disease. Neuroimaging biomarkers represent powerful additions to the current monitoring repertoire but have yiel...

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Bibliographic Details
Main Authors: Robert Steinbach, Meerim Batyrbekova, Nayana Gaur, Annika Voss, Beatrice Stubendorff, Thomas E. Mayer, Christian Gaser, Otto W. Witte, Tino Prell, Julian Grosskreutz
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158219304413