Hypoxia-Responsive Mesoporous Nanoparticles for Doxorubicin Delivery
Hypoxia, or low oxygen tension, is a common feature of solid tumors. Here, we report hypoxia-responsive mesoporous silica nanoparticles (HR-MSNs) with a 4-nitroimidazole-β-cyclodextrin (NI-CD) complex that is acting as the hypoxia-responsive gatekeeper. When these CD-HR-MSNs encountered a hypoxic en...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-04-01
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Series: | Polymers |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4360/10/4/390 |