Hypoxia-Responsive Mesoporous Nanoparticles for Doxorubicin Delivery

Hypoxia-Responsive Mesoporous Nanoparticles for Doxorubicin Delivery

Hypoxia, or low oxygen tension, is a common feature of solid tumors. Here, we report hypoxia-responsive mesoporous silica nanoparticles (HR-MSNs) with a 4-nitroimidazole-β-cyclodextrin (NI-CD) complex that is acting as the hypoxia-responsive gatekeeper. When these CD-HR-MSNs encountered a hypoxic en...

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Bibliographic Details
Main Authors: Shakera Khatoon, Hwa Seung Han, Jueun Jeon, N. Vijayakameswara Rao, Dae-Woong Jeong, M. Ikram, T. Yasin, Gi-Ra Yi, Jae Hyung Park
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Polymers
Subjects:
hypoxia
mesoporous silica nanoparticles
nitroimidazole
β-cyclodextrin
doxorubicin
Online Access:http://www.mdpi.com/2073-4360/10/4/390

Internet

http://www.mdpi.com/2073-4360/10/4/390

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